|The full article is available to subscribers||Subscriber Login|
The nasal spray formulation of the corticosteroid fluticasone propionate is now available over the counter (OTC) as Flonase Allergy Relief (GSK) in the same strength as the prescription product (Flonase, and generics) for patients ≥4 years old with seasonal or perennial allergic rhinitis. It is the second corticosteroid nasal spray to become available OTC; triamcinolone acetonide (Nasacort Allergy 24HR) was the first.1 Unlike prescription Flonase, the OTC product is FDA-approved for reduction of ocular as well as nasal symptoms. Brand-name prescription Flonase has been discontinued by the manufacturer.
CLINICAL USE — Intranasal corticosteroids are the most effective drugs available for prevention and relief of seasonal allergic rhinitis symptoms, including itching, sneezing, discharge, and congestion. They are also effective in reducing... more
- An OTC corticosteroid nasal spray for allergic rhinitis. Med Lett Drugs Ther 2013; 55:90.
- Drugs for allergic disorders. Treat Guidel Med Lett 2013; 11:43.
- M Benninger et al. Evaluating approved medications to treat allergic rhinitis in the United States: an evidence-based review of efficacy for nasal symptoms by class. Ann Allergy Asthma Immunol 2010; 104:13.
- P Ratner et al. Efficacy of daily intranasal fluticasone propionate on ocular symptoms associated with seasonal allergic rhinitis. Ann Allergy Asthma Immunol 2015; 114:141.
- GH Chang and WH Wang. Intranasal fungal (Alternaria) infection related to nasal steroid spray. Am J Otolaryngol 2013; 34:743.
- J Sastre and R Mosges. Local and systemic safety of intranasal corticosteroids. J Investig Allergol Clin Immunol 2012; 22:1.
- DP Skoner et al. Intranasal triamcinolone and growth velocity. Pediatrics 2015; 135:e348.