The Medical Letter article on
Detrol LA and
Ditropan XL (vol.43, page 28, April 2, 2001) stated that these drugs should not be used in patients with glaucoma. That statement is misleading because anticholinergic or antimuscarinic drugs present a risk only to patients with untreated angle-closure (also called narrow-angle) glaucoma, which accounts for 10% of glaucomas in the USA. These drugs have no effect on the more common open-angle glaucoma, or on angle-closure glaucoma that has been treated by laser iridectomy.
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Information about the article:
Title: Clarification: Drug Risk in Patients with Glaucoma
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 1106
Article Code: 1106c
Date: June 11, 2001
Volume: 43
Page: 52
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