Gamma Hydroxybutyrate (Xyrem) for Narcolepsy
The FDA has approved use of gamma hydroxybutyrate (sodium oxybate is the official generic name; Xyrem - Orphan Medical) for oral treatment of cataplexy in patients with narcolepsy. Gamma hydroxybutyrate (GHB), a metabolite of gamma-aminobutyric acid (GABA), is a central-nervous-system depressant marketed in Europe for use in general anesthesia. In recent years it has been notorious for its use in "date-rape" (Medical Letter 2002; 44:21). Xyrem is a Schedule III controlled substance....
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Title: Gamma Hydroxybutyrate (Xyrem) for Narcolepsy
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 1145
Article Code: 1145a
Date: December 9, 2002
Volume: 44
Pages: 103-105
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 1145
Article Code: 1145a
Date: December 9, 2002
Volume: 44
Pages: 103-105
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