Adefovir dipivoxil (Hepsera - Gilead), a nucleotide analog, has been approved by the FDA for oral treatment of chronic active infection with hepatitis B virus (HBV). In 1999, because of concerns about renal toxicity, the FDA rejected a higher-dosage formulation of adefovir for treatment of HIV infection....
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Information about the article:
Title: Adefovir (Hepsera) for Chronic Hepatitis B Infection
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 1145
Article Code: 1145b
Date: December 9, 2002
Volume: 44
Pages: 105-106