Zolpidem (Ambien - Sanofi-Aventis), a nonbenzodiazepine benzodiazepine receptor agonist, is the most frequently prescribed hypnotic in the US. As its patent approaches expiration, its manufacturer has received FDA approval to market an extended-release formulation of the drug, Ambien CR. The pharmacological rationale for doing so is that short-acting hypnotics like zolpidem are more effective at inducing sleep than they are at maintaining it....
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Information about the article:
Title: Ambien CR for Insomnia
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 1223
Article Code: 1223a
Date: December 5, 2005
Volume: 47
Pages: 97-98