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Wellbutrin Versus Generic Bupropion

Bupropion (Wellbutrin - GlaxoSmithKline, and others) is a norepinephrine and dopamine reuptake inhibitor that has been a useful antidepressant because, unlike some other antidepressants, it does not cause sexual dysfunction, weight gain or sedation. Some patients who were switched from Wellbutrin to a generic alternative have reported worsening side effects and relapse of previously controlled depressive symptoms.1 Most of the complaints have come from patients switched from Wellbutrin XL 300 mg to the generic 300-mg formulation of extended-release bupropion marketed by Teva (Budeprion XL).2 In 2007, about 1 million prescriptions per month were dispensed for extended-release formulations of bupropion; about 40% of these were written for Budeprion XL 300 mg....
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Information about the article:
Title: Wellbutrin Versus Generic Bupropion
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 1290
Article Code: 1290c
Date: July 14, 2008
Volume: 50
Pages: 54-55

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