A 0.75% vaginal gel formulation of metronidazole (MetroGel-Vaginal - Curatek) and a 2% vaginal cream formulation of clindamycin phosphate (Cleocin - Upjohn) were recently approved by the US Food and Drug Administration for treatment of bacterial vaginosis. Seven days' treatment with oral metronidazole, 500 mg b.i.d., has been the usual treatment for this condition, with oral clindamycin, 300 mg b.i.d., as an alternative (JL Thomason et al, Am J Obstet Gynecol, 165:1210, 1991)....
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Information about the article:
Title: Topical Treatment for Bacterial Vaginosis
Publication: The Medical Letter on Drugs and Therapeutics
Issue #: 884
Article Code: 884b
Date: November 27, 1992
Volume: 34
Pages: 109-110