Treatment Guidelines from The Medical Letter
Antithrombotic Drugs
Subscribers: Log in to read full article.  Not a subscriber?  Subscribe or purchase article.
Updated March 2012

Arterial thrombi are composed mainly of platelet aggregates held together by small amounts of fibrin. Antiplatelet drugs are the drugs of choice for prevention and treatment of arterial thrombosis, but anticoagulants are also effective, and their effects can add to those of antiplatelet drugs. Venous thrombi are composed mainly of fibrin and trapped red blood cells, with relatively few platelets. Anticoagulants are the agents of choice for prevention and treatment of venous thromboembolism and for prevention of cardioembolic events in patients with atrial fibrillation.


Antiplatelet drugs are used mainly for primary and secondary prevention and treatment of acute coronary syndrome (ACS), which includes unstable angina/non- ST-elevation myocardial infarction (UA/NSTEMI), ST-elevation myocardial infarction (STEMI) and percutaneous coronary intervention (PCI).

ASPIRIN — ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

Would you like to read the rest of this article?  Gain access below.

Subscriptions to The Medical Letter on Drugs and Therapeutics include:
  • Print version published and mailed biweekly (26 issues/year)
  • Unlimited online access to current and past issues (1988 - present)
  • Mobile App for iOS, Android, and Kindle Fire
  • FREE online per issue CME/CE
Purchase this article:
Title: Antithrombotic Drugs
Article code: 110a
 Electronic, downloadable article - $45
Gain access through your organization
Ask your librarian to consider an Institutional Subscription to The Medical Letter.
Recommend to your librarian