Treatment Guidelines from The Medical Letter
Drugs for Inflammatory Bowel Disease
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RECOMMENDATIONSUlcerative Colitis – An aminosalicylate is generally used first for treatment and maintenance of remission. Mercaptopurine or azathioprine is often used in patients with moderate to severe disease. Prednisone can be used to treat severe relapses. Patients with treatment-refractory disease may respond to a TNF inhibitor, such as infliximab.Crohn’s Disease – Prednisone can be used to induce remission. Azathioprine or mercaptopurine is often used for maintenance of remission. Moderate to severe Crohn’s disease that has not responded to other drugs may respond to a TNF inhibitor, such as infliximab. Some clinicians would use a TNF inhibitor alone or in combination with azathioprine for initial treatment of moderate to severe disease. Metronidazole or ciprofloxacin may be helpful in some patients. Methotrexate is an alternative for patients with steroid-resistant or ... more      
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Title: Drugs for Inflammatory Bowel Disease
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