The Medical Letter on Drugs and Therapeutics
Olopatadine (Patanase) Nasal Spray
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Olopatadine 0.6% nasal spray (Patanase – Alcon) has been approved by the FDA for treatment of seasonal allergic rhinitis in patients ≥12 years old. An H1- antihistamine with mast-cell stabilizing activity, olopatadine is already marketed for treatment of allergic conjunctivitis in a 0.1% solution as Patanol and in a 0.2% solution as Pataday. Azelastine (Astelin), another H1-antihistamine with mast-cell stabilizing activity, has been available for intranasal treatment of allergic rhinitis since 1997.

DRUGS FOR ALLERGIC RHINITIS — A variety of oral and topical drugs are marketed for treatment of allergic rhinitis.1 An oral second-generation H1-antihistamine is often used for treatment of mild to moderate disease; loratadine (Claritin, and others), fexofenadine (Allegra, and others) and cetirizine (Zyrtec, ... more      

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Title: Olopatadine (Patanase) Nasal Spray
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