The Medical Letter on Drugs and Therapeutics
Laser Treatment of Onychomycosis
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Fungal infections of the fingernails or toenails can persist for months or years despite topical and systemic antimicrobial therapy.1 The FDA has cleared several short-pulse laser systems for treatment of this mainly cosmetic disorder.2

MECHANISM OF ACTION — Fungi are heat sensitive. Sustained heating at the temperatures achieved in the nail and nail bed by lasers with wavelengths in the near-infrared spectrum is fungicidal.3

EFFICACY — The results of some small, uncontrolled studies in patients with onychomycosis suggest that use of lasers can increase clear linear nail growth.4 In one 3 month trial in 7 patients, 4 of 13 nails showed >25% improvement after 2 laser treatments given 6 weeks apart.5 A study ... more      

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Title: Laser Treatment of Onychomycosis
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