The Medical Letter on Drugs and Therapeutics
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Influenza Vaccine for 2013-2014

Annual vaccination against influenza A and B viruses has been shown to decrease influenza illness and its complications. Several new vaccines are available for the current season.

VACCINE COMPOSITION — This year's seasonal trivalent influenza vaccines contain the following three strains: A/California/7/2009 H1N1-like, A/Victoria/361/2011 H3N2-like, and B/Massachusetts/2/2012-like. Quadrivalent vaccines will also include B/Brisbane/60/2008-like to provide additional protection against influenza B viruses.1

LIVE VS. INACTIVATED VACCINE — The intranasal live-attenuated influenza vaccine (LAIV), FluMist Quadrivalent, is recommended for use only in healthy, non-pregnant persons 2-49 years old. In children, the LAIV appears to be more effective than the inactivated influenza vaccine (IIV).2 In adults, the IIV has been ... more      

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