The Medical Letter on Drugs and Therapeutics
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1467
Pomalidomide (Pomalyst) for Multiple Myeloma (online only)
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The FDA has approved pomalidomide (Pomalyst – Celgene), an oral thalidomide analog, for treatment of patients with multiple myeloma who have received at least 2 prior therapies including lenalidomide (Revlimid) and bortezomib (Velcade) and whose disease had progressed on or within 60 days of completion of the last therapy.

MULTIPLE MYELOMA — Use of drug regimens that include bortezomib,1 a proteasome inhibitor, plus thalidomide (Thalomid) or lenalidomide,2 another thalidomide analog, has led to improved response rates and survival in patients with multiple myeloma. Carfilzomib (Kyprolis),3 a second proteasome inhibitor, is approved for treatment of refractory multiple myeloma. Many patients do not respond to these drugs ... more      

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