The Medical Letter on Drugs and Therapeutics
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1495
Three New Drugs for Multiple Myeloma (online only)
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The FDA recently approved ixazomib (Ninlaro – Takeda), daratumumab (Darzalex – Janssen Biotech), and elotuzumab (Empliciti – BMS) for treatment of relapsed and/or refractory multiple myeloma.

STANDARD TREATMENT — Use of drug regimens that include the proteasome inhibitor bortezomib (Velcade) plus either the immunomodulating drug thalidomide (Thalomid) or lenalidomide (Revlimid), a thalidomide analog, instead of chemotherapy has led to improved response rates and survival in patients with multiple myeloma.

Carfilzomib (Kyprolis), a second proteasome inhibitor, is an alternative for treatment of refractory multiple myeloma.1 Pomalidomide (Pomalyst), another thalidomide analog, is an alternative for patients with disease progression who have received at least two prior therapies including ... more      

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Title: Three New Drugs for Multiple Myeloma (online only)
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