The Medical Letter on Drugs and Therapeutics
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1515
Atezolizumab (Tecentriq) for Bladder Cancer and NSCLC (online only)
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The FDA has approved the immune checkpoint inhibitor atezolizumab (Tecentriq – Genentech) for treatment of locally advanced or metastatic urothelial carcinoma and metastatic non-small cell lung cancer (NSCLC) that have progressed during or following platinum-based chemotherapy. Atezolizumab is the first programmed death-ligand 1 (PD-L1) blocking antibody to become available in the US. Two other immune checkpoint inhibitors, the programmed death receptor-1 (PD-1) inhibitors nivolumab (Opdivo) and pembrolizumab (Keytruda), are also approved for treatment of metastatic NSCLC, and nivolumab is also approved for second-line treatment of locally advanced or metastatic urothelial carcinoma.

UROTHELIAL CARCINOMA — Urothelial carcinoma (also known as transitional cell carcinoma) is the most common type of bladder cancer in the US. Most urothelial cancers of the bladder are superficial ... more      

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Title: Atezolizumab (Tecentriq) for Bladder Cancer and NSCLC (online only)
Article code: 1515g
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