The Medical Letter on Drugs and Therapeutics
Drugs for Hypertension
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Drugs available for treatment of chronic hypertension in the US and their dosages, adverse effects, and costs are listed in the tables. Treatment of hypertensive urgencies and emergencies is not discussed here.

NEW BLOOD PRESSURE GOALS — Previously published guidelines recommend a blood pressure goal of 140/90 mm Hg for most patients with hypertension and 150/90 mm Hg for some patients ≥60 years old, but new data have recently become available.

With the publication of the Systolic Blood Pressure Intervention trial (SPRINT), the systolic blood pressure goal of <140 mm Hg may be lowered for some patients. In SPRINT, patients >50 years old with a systolic blood pressure of 130-180 mm Hg and an increased cardiovascular risk (but without diabetes or a history of stroke) were randomized to a systolic blood pressure target of <120 mm Hg (intensive treatment) or <140 mm Hg (standard treatment). ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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Title: Drugs for Hypertension
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