The Medical Letter on Drugs and Therapeutics
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1521
Issue 1521
Prescription Drug Prices in the US; Valbenazine (Ingrezza) for Tardive Dyskinesia; Oxymetazoline Cream (Rhofade) for Rosacea; FDA Warns Against Use of Codeine and Tramadol in Children and Breastfeeding Women; Another Subcutaneous Immune Globulin (Cuvitru) for Primary Immunodeficiency (online only); Vonvendi - Recombinant von Willebrand Factor (online only); Comparison Table: Some Topical Drugs for Rosacea (online only)
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Prescription Drug Prices in the US

Per capita spending on prescription drugs in the US is higher than in other industrialized nations, including Canada.1

OTHER COUNTRIES — In most industrialized countries, unlike the US, drug prices are regulated by the government. Centralized advisory boards determine the clinical efficacy and cost-effectiveness of a drug. Prices are based in part on external price referencing (comparison of drug prices in several countries to determine a reference price) and are often transparent and capped.2 Fewer payers are involved, and in some countries, there is only a single public payer.

LIST PRICE vs NEGOTIATED PRICE — Drug pricing in the US is complicated by multiple factors, including list prices that do not reflect what is actually paid for a drug, the number of middlemen involved in getting a drug from the manufacturer to ... more       Show References Hide References

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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