The Medical Letter on Drugs and Therapeutics
Issue 1525
Drugs for Helicobacter pylori Infection; Brodalumab (Siliq) - Another IL-17A Antagonist for Psoriasis; Telotristat Ethyl (Xermelo) for Carcinoid Syndrome Diarrhea; In Brief: Avelumab (Bavencio) for Metastatic Merkel Cell Carcinoma (online only)
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Drugs for Helicobacter pylori Infection

About 50% of the world’s population is infected with Helicobacter pylori. These gastric bacteria can cause chronic inflammation and have been associated with development of gastritis, peptic ulcer disease, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma.1 Eradication of H. pylori can promote gastric healing, prevent recurrence of duodenal and gastric ulcers, and reduce the incidence of gastric cancer.2,3 Guidelines for treatment of H. pylori infection were updated recently.4-6

NONINVASIVE TESTING — Urea Breath Tests – A urea breath test (BreathTek; BreathID; PYtest) can be used for office-based diagnosis of H. pylori infection. The patient ingests a urea solution or urea-containing capsule labeled with a carbon ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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