Treatment Guidelines from The Medical Letter
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77
Drugs for Hypertension
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Drugs available in the US for treatment of chronic hypertension, with their dosages, adverse effects and costs, are listed in the tables that begin on page 2. Combination products are listed on page 9. Drugs for treatment of hypertensive emergencies are not discussed here. They were reviewed in Treatment Guidelines (volume 1, page 19, December 2002) and in The Medical Letter (volume 50, page 73, September 22, 2008).

DIURETICS

Thiazide-type diuretics are the first-line therapy for many patients with hypertension. Hydrochlorothiazide and chlorthalidone are the most widely used. In a double-blind, randomized controlled trial (ALLHAT) in more than 30,000 men and women more than 55 years old with hypertension and at least one risk factor for coronary heart disease, chlorthalidone ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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