Treatment Guidelines from The Medical Letter
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98
Drugs for Non-HIV Viral Infections
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The drugs of choice for treatment of non-HIV viral infections and their dosages are listed in Tables 1-6 on the pages that follow. Some of the indications and dosages recommended here have not been approved by the FDA. Vaccines used for the prevention of viral infections are discussed in another issue of Treatment Guidelines.1

DRUGS FOR HERPES SIMPLEX AND VARICELLA-ZOSTER VIRUS

ACYCLOVIR (Zovirax, and others) — Available in topical, oral and intravenous (IV) formulations, acyclovir is used to treat herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections. Topical acyclovir cream reduces the duration of orolabial herpes by about 0.5 days. Oral acyclovir can shorten the duration of symptoms in primary orolabial, genital and anorectal HSV infections, and to a lesser extent in recurrent orolabial and genital HSV infections. Long-term oral suppression ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

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