Matching articles for "Mirena"
Choice of Contraceptives
The Medical Letter on Drugs and Therapeutics • May 15, 2023; (Issue 1676)
Intrauterine devices (IUDs) and the etonogestrel
implant are the most effective reversible contraceptive
methods available. Hormonal oral contraceptives,
patches, rings, and injectables are also effective...
Intrauterine devices (IUDs) and the etonogestrel
implant are the most effective reversible contraceptive
methods available. Hormonal oral contraceptives,
patches, rings, and injectables are also effective in
preventing pregnancy. When used alone, barrier and
behavioral methods generally have higher failure
rates than other methods (see Table 1). Selection of
a contraceptive method is usually based on patient-specific factors and personal preference
Myfembree for Fibroid-Associated Heavy Menstrual Bleeding
The Medical Letter on Drugs and Therapeutics • August 9, 2021; (Issue 1630)
Myfembree (Myovant/Pfizer), an oral fixed-dose
combination of the gonadotropin-releasing hormone
(GnRH) receptor antagonist relugolix, the estrogen
estradiol, and the progestin norethindrone acetate,
has...
Myfembree (Myovant/Pfizer), an oral fixed-dose
combination of the gonadotropin-releasing hormone
(GnRH) receptor antagonist relugolix, the estrogen
estradiol, and the progestin norethindrone acetate,
has been approved by the FDA for management of
heavy menstrual bleeding associated with uterine
leiomyomas (fibroids) in premenopausal women. It is
the second product to be approved in the US for this
indication; Oriahnn, which contains the GnRH receptor
antagonist elagolix in combination with estradiol and
norethindrone acetate, was approved earlier. Relugolix
was approved for treatment of advanced prostate
cancer as Orgovyx in 2020.
Oriahnn for Fibroid-Associated Heavy Menstrual Bleeding
The Medical Letter on Drugs and Therapeutics • April 5, 2021; (Issue 1621)
Oriahnn (Abbvie), a fixed-dose combination of the
gonadotropin-releasing hormone (GnRH) receptor
antagonist elagolix, the estrogen estradiol, and the
progestin norethindrone acetate copackaged with
elagolix...
Oriahnn (Abbvie), a fixed-dose combination of the
gonadotropin-releasing hormone (GnRH) receptor
antagonist elagolix, the estrogen estradiol, and the
progestin norethindrone acetate copackaged with
elagolix alone, has been approved by the FDA for oral
treatment of heavy menstrual bleeding associated
with uterine leiomyomas (fibroids) in premenopausal
women. It is the first product to be approved in the
US for this indication. Elagolix (Orilissa) has been
available since 2018 for treatment of moderate to
severe pain associated with endometriosis. The
GnRH receptor antagonist relugolix (Orgovyx), which is
approved for treatment of advanced prostate cancer,
is being reviewed by the FDA for use in combination
with estradiol and norethindrone acetate for the same
indication as Oriahnn.
Phexxi - A Nonhormonal Contraceptive Gel
The Medical Letter on Drugs and Therapeutics • August 24, 2020; (Issue 1605)
The FDA has approved Phexxi (Evofem), a
nonhormonal prescription-only vaginal gel containing
lactic acid, citric acid, and potassium bitartrate, for
prevention of pregnancy. The gel is intended for...
The FDA has approved Phexxi (Evofem), a
nonhormonal prescription-only vaginal gel containing
lactic acid, citric acid, and potassium bitartrate, for
prevention of pregnancy. The gel is intended for on-demand
contraception; it is not effective when used
after intercourse. It was previously approved for
use as a vaginal lubricant (Amphora), but was never
marketed.
Choice of Contraceptives
The Medical Letter on Drugs and Therapeutics • October 8, 2018; (Issue 1557)
Intrauterine devices (IUDs) and the etonogestrel
implant are the most effective reversible contraceptive
methods available. Hormonal oral contraceptives,
patches, rings, and injectables are also highly...
Intrauterine devices (IUDs) and the etonogestrel
implant are the most effective reversible contraceptive
methods available. Hormonal oral contraceptives,
patches, rings, and injectables are also highly effective
in preventing pregnancy. When used alone, barrier and
fertility-based methods generally have higher failure
rates than other methods.
Kyleena - Another Hormonal IUD
The Medical Letter on Drugs and Therapeutics • February 27, 2017; (Issue 1515)
The FDA has approved Kyleena (Bayer), an intrauterine
device (IUD) that releases the synthetic progestin
levonorgestrel, for prevention of pregnancy. It is the
fourth levonorgestrel-releasing IUD to be...
The FDA has approved Kyleena (Bayer), an intrauterine
device (IUD) that releases the synthetic progestin
levonorgestrel, for prevention of pregnancy. It is the
fourth levonorgestrel-releasing IUD to be approved in
the US. Like Mirena, which has been available since
2000, Kyleena is approved for up to 5 years of use.
Choice of Contraceptives
The Medical Letter on Drugs and Therapeutics • September 14, 2015; (Issue 1477)
Implants, intrauterine devices (IUDs), and sterilization
are the most effective contraceptive methods available.
Pills, patches, rings, and injectables, when used
correctly, are also highly effective in...
Implants, intrauterine devices (IUDs), and sterilization
are the most effective contraceptive methods available.
Pills, patches, rings, and injectables, when used
correctly, are also highly effective in preventing pregnancy.
Barrier and fertility-based methods have the
highest rates of failure.
Liletta - A Third Levonorgestrel-Releasing IUD
The Medical Letter on Drugs and Therapeutics • July 6, 2015; (Issue 1472)
The FDA has approved Liletta, an intrauterine
device (IUD) that releases the synthetic progestin
levonorgestrel, for prevention of pregnancy for up to
3 years. The fourth IUD to be approved in the US,...
The FDA has approved Liletta, an intrauterine
device (IUD) that releases the synthetic progestin
levonorgestrel, for prevention of pregnancy for up to
3 years. The fourth IUD to be approved in the US, and
the third that releases levonorgestrel, Liletta is
comarketed by Actavis and Medicines360, a nonprofit
women's health pharmaceutical company. The wholesale
cost of Liletta is similar to that of other IUDs (see
Table 1), but the manufacturer offers programs that
significantly reduce the cost for commercially-insured
patients and clinics serving low-income women.
A New Low-Dose Levonorgestrel-Releasing IUD (Skyla)
The Medical Letter on Drugs and Therapeutics • March 18, 2013; (Issue 1412)
The FDA recently approved Skyla (Bayer), the first new
intrauterine device (IUD) in the US in 12 years. It
releases levonorgestrel, a synthetic progestin, over a
period of 3 years. A table summarizing...
The FDA recently approved Skyla (Bayer), the first new
intrauterine device (IUD) in the US in 12 years. It
releases levonorgestrel, a synthetic progestin, over a
period of 3 years. A table summarizing contraceptive
methods available in the US appears on page 22.
Choice of Contraceptives
The Medical Letter on Drugs and Therapeutics • December 1, 2010; (Issue 100)
The choice of which contraceptive to use may vary from one stage of reproductive life to another. Intrauterine devices (IUDs), progestin implants and sterilization are the most effective contraceptive methods...
The choice of which contraceptive to use may vary from one stage of reproductive life to another. Intrauterine devices (IUDs), progestin implants and sterilization are the most effective contraceptive methods available to women. Hormonal contraceptives, when used correctly, are also highly effective in preventing pregnancy. Barrier and fertility-based methods
have the highest rate of failure.
Tranexamic Acid (Lysteda) for Treatment of Menorrhagia
The Medical Letter on Drugs and Therapeutics • July 12, 2010; (Issue 1342)
The FDA has approved the use of tranexamic acid (Lysteda – Ferring), an oral antifibrinolytic, for treatment of menorrhagia. Tranexamic acid has been used for this purpose in Europe for decades, and is...
The FDA has approved the use of tranexamic acid (Lysteda – Ferring), an oral antifibrinolytic, for treatment of menorrhagia. Tranexamic acid has been used for this purpose in Europe for decades, and is available without a prescription in some countries. It has been available in the US since 1987 for use with coagulation factors in patients with hemophilia undergoing dental extractions.
Choice of Contraceptives
The Medical Letter on Drugs and Therapeutics • December 1, 2007; (Issue 64)
Transdermal, transvaginal and intrauterine hormone delivery systems have made highly effective contraceptive products more convenient to use. New oral contraceptive options include regimens with fewer or...
Transdermal, transvaginal and intrauterine hormone delivery systems have made highly effective contraceptive products more convenient to use. New oral contraceptive options include regimens with fewer or shorter hormone-free intervals.
Treatment of Menopausal Vasomotor Symptoms
The Medical Letter on Drugs and Therapeutics • December 6, 2004; (Issue 1197)
Estrogen is the most effective treatment for menopausal vasomotor symptoms (hot flashes), but the Women's Health Initiative study found that women who took estrogen plus a progestin for more than 5 years were...
Estrogen is the most effective treatment for menopausal vasomotor symptoms (hot flashes), but the Women's Health Initiative study found that women who took estrogen plus a progestin for more than 5 years were at increased risk for myocardial infarction, stroke, pulmonary emboli, deep vein thrombosis, breast cancer, and possibly dementia. Are there effective alternatives?
A Progestin-Releasing Intrauterine Device For Long-Term Contraception
The Medical Letter on Drugs and Therapeutics • January 22, 2001; (Issue 1096)
The FDA had approved an intrauterine contraceptive device that releases the synthetic progestin levonorgestrel over a period of five years. The device has been available in Europe for 10...
The FDA had approved an intrauterine contraceptive device that releases the synthetic progestin levonorgestrel over a period of five years. The device has been available in Europe for 10 years.