Irritable bowel syndrome (IBS) is a common disorder characterized by chronic, intermittent abdominal pain or discomfort and altered bowel habits.1 It is subtyped according to the predominant bowel symptom as IBS with constipation (IBS-C), IBS with diarrhea (IBS-D), mixed type (IBS-M), or unclassified (IBS-U).2 Since the exact cause of IBS is unknown, the goal of treatment is symptom control.3
DIET — Many patients with IBS report symptoms associated with meals or specific foods.4 Avoidance of gluten, gas-producing foods, and fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) may be effective in reducing some IBS symptoms.5-8 FODMAPs are poorly absorbed, rapidly fermented short-chain carbohydrates that can increase gas production and induce osmosis in the...
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Differin Gel 0.1% (Galderma), a topical formulation of the retinoid adapalene, will soon be available over the counter (OTC) for once-daily treatment of acne in patients ≥12 years old. It is the first topical retinoid to be approved for sale over the counter.
All topical retinoids normalize keratinization and appear to have anti-inflammatory effects; whether any one topical retinoid is more effective than any other is not clear. Many dermatologists now recommend topical retinoids for first-line treatment of acne; they can be used alone or in combination with antibiotics to ...