Treatment of Migraine
An oral nonopioid analgesic may be sufficient for treatment of mild to moderate migraine without severe nausea or vomiting. A triptan is the drug of choice for treatment of moderate to severe migraine.1,2 Use of a triptan early in an attack when pain is still mild to moderate in intensity improves headache response and reduces recurrence rates.
ANALGESICS – Aspirin and acetaminophen, used alone or together in combination with caffeine (Excedrin Migraine, and others), and nonsteroidal anti-inflammatory drugs (NSAIDs) such as naproxen sodium (Aleve, and others) and ibuprofen (Advil, Motrin, and generics) are effective in relieving mild to moderate migraine pain.3-5 The NSAID diclofenac is FDA-approved as a powder for oral solution (Cambia) for treatment of migraine; it has a rapid onset of...
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Auvi-Q (Kaléo; previously manufactured and marketed by Sanofi), the epinephrine auto-injector approved by the FDA in 2012 for emergency treatment of anaphylaxis and voluntarily withdrawn in 2015 due to potential inaccurate dosage delivery,1 has become available once more. According to Kaléo, improvements in the manufacturing process have addressed the concerns that led to its recall.