Patients with seasonal allergies often experience nasal itching and congestion, sneezing, rhinorrhea, and itchy, watery eyes. Oral, intranasal, and ophthalmic preparations are widely available over the counter (OTC) for relief of symptoms. Prescription products for management of allergic rhinitis and allergic conjunctivitis are reviewed separately....  Continue reading
More from Issue 1570
Previous Issue: 1569      April 8, 2019
Coming Soon
PrabotulinumtoxinA (Jeuveau) for Frown Lines
Drugs for Psoriasis
Omadacycline (Nuzyra) - A New Tetracycline Antibiotic
Insulins for Type 2 Diabetes
Brexanolone (Zulresso) for Postpartum Depression
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Eravacycline (Xerava – Tetraphase), a new synthetic tetracycline antibiotic, has been approved by the FDA for IV treatment of complicated intra-abdominal infections (cIAIs) in adults. Eravacycline is structurally similar to tigecycline (Tygacil, and generics), a broad-spectrum tetracycline approved by the FDA for IV treatment of complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired pneumonia. A higher rate of mortality has been reported with use of tigecycline compared to other antibacterial drugs; it should be used only when no suitable alternative is available.1

ACTIVITY — Eravacycline, like other tetracyclines, binds to the bacterial 30S ribosomal subunit, inhibiting protein ... Continue reading