Drugs for Inflammatory Bowel Disease | The Medical Letter Inc.

Treatment Guidelines from The Medical Letter

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115

March 1, 2012

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Drugs for Inflammatory Bowel Disease

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Drugs for Inflammatory Bowel Disease

March 1, 2012 (Issue: 115)

Superseded by The Medical Letter "Drugs for Inflammatory Bowel Disease" - Issue 1680, July 10, 2023

Inflammatory bowel disease (IBD) is generally classified as either Crohn’s disease (CD) or ulcerative colitis (UC). More detailed guidelines on their treatment are available from the American College of Gastroenterology.

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2. A Kornbluth et al. Ulcerative colitis practice guidelines in adults: American College of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol 2010; 105:501.

3. C Campregher and C Gasche. Aminosalicylates. Best Pract Res Clin Gastroenterol 2011; 25:535.

4. Once-daily mesalamine (Lialda) for ulcerative colitis. Med Lett Drugs Ther 2007; 49:25.

5. Encapsulated mesalamine granules (Apriso) for ulcerative colitis. Med Lett Drugs Ther 2009; 51:38.

6. P Marteau et al. Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study. Gut 2005; 54:960.

7. AC Ford et al. Efficacy of 5-aminosalicylates in Crohn’s disease: systematic review and meta-analysis. Am J Gastroenterol 2011; 106:617.

8. KJ Khan et al. Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol 2011; 106:661.

9. GT Ho et al. The efficacy of corticosteroid therapy in inflammatory bowel disease: analysis of a 5-year UK inception cohort. Aliment Pharmacol Ther 2006; 24:319.

10. AH Steinhart et al. Corticosteroids for maintenance of remission in Crohn’s disease. Cochrane Database Syst Rev 2003; (4): CD000301.

11. Budesonide (Entocort EC) for Crohn’s disease. Med Lett Drugs Ther 2002; 44:6.

12. AG Fraser et al. The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002; 50:485.

13. JF Colombel et al. Infliximab, azathioprine, or combination therapy for Crohn’s disease. N Engl J Med 2010; 362:1383.

14. L Peyrin-Biroulet et al. Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology 2011; 141:1621.

15. L Beaugerie et al. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet 2009; 374:1617.

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24. Certolizumab (Cimzia) for Crohn’s disease. Med Lett Drugs Ther 2008; 50:81.

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32. JF Colombel et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn’s disease: the CHARM trial. Gastroenterology 2007; 132:52.

33. S Schreiber et al. Maintenance therapy with certolizumab pegol for Crohn’s disease. N Engl J Med 2007; 357:239.

34. L Peyrin-Biroulet et al. Efficacy and safety of tumor necrosis factor antagonists in Crohn’s disease: meta-analysis of placebo-controlled trials. Clin Gastroenterol Hepatol 2008; 6:644.

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36. S Danese et al. Successful induction of clinical response and remission with certolizumab pegol in Crohn’s disease patients refractory or intolerant to infliximab: a real-life multicenter experience of compassionate use. Inflamm Bowel Dis 2008; 14:1168.

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38. W Reinisch et al. Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut 2011; 60:780.

39. WJ Sandborn et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology 2012; 142:257.

40. WJ Sandborn et al. Natalizumab induction and maintenance therapy for Crohn’s disease. N Engl J Med 2005; 353:1912.

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48. W Kruis et al. Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissile 1917 is as effective as with standard mesalazine. Gut 2004; 53:1617.

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