The Medical Letter on Drugs and Therapeutics
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1515
February 27, 2017
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Drug Interaction: Clopidogrel and PPIs
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Drug Interaction: Clopidogrel and PPIs
February 27, 2017 (Issue: 1515)
The antiplatelet drug clopidogrel (Plavix, and others) reduces major cardiovascular events, but can cause bleeding. Proton pump inhibitors (PPIs) are often used with clopidogrel to prevent gastrointestinal bleeding, however, some evidence...more
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