Two New Pneumococcal Vaccines - Prevnar 20 and Vaxneuvance
Two New Pneumococcal Vaccines - Prevnar 20 and Vaxneuvance
November 29, 2021 (Issue: 1638)
The FDA has licensed two new pneumococcal
conjugate vaccines (PCVs) for prevention of invasive
pneumococcal disease in adults: Prevnar 20 (PCV20;
Pfizer), which contains antigens from 20 serotypes of
pneumococcus, and Vaxneuvance (PCV15;...more
- Adult immunization. Med Lett Drugs Ther 2018; 60:73.
- S Tomczyk et al. Use of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine among adults aged ≥65 years: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Morb Mortal Wkly Rep 2014; 63:822.
- ME Pichichero. Protein carriers of conjugate vaccines: characteristics, development, and clinical trials. Hum Vaccin Immunother 2013; 9:2505.
- M Kobayashi. Considerations for age-based and risk-based use of PCV15 and PCV20 among U.S. adults and proposed policy options. ACIP Meeting. October 20, 2021. Available at: https://bit. ly/2YhkaOi. Accessed November 10, 2021.
- MJM Bonten et al. Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults. N Engl J Med 2015; 372:1114.
- D Hurley et al. Safety, tolerability, and immunogenicity of a 20-valent pneumococcal conjugate vaccine (PCV20) in adults 60 to 64 years of age. Clin Infect Dis 2021; 73:e1489.
- HL Platt et al. A phase 3 trial of safety, tolerability, and immunogenicity of V114, 15-valent pneumococcal conjugate vaccine, compared with 13-valent pneumococcal conjugate vaccine in adults 50 years of age and older (PNEU-AGE). Vaccine 2021 September 7 (epub).
- JY Song et al. Safety, tolerability, and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine, followed by sequential PPSV23 vaccination in healthy adults aged ≥50 years: a randomized phase III trial (PNEU-PATH). Vaccine 2021; 39:6422.
- American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 741: maternal immunization. Obstet Gynecol 2018; 131:e214.
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