The Interruption of Anticoagulation section of our article on Treatment of Atrial Fibrillation cited the recommendations of the American College of Chest Physicians on perioperative management of antithrombotic therapy (JD Douketis et al. Chest 2022; 162:e207). A reader suggested that our general statement on when to discontinue an oral anticoagulant would have benefited from inclusion of the recommendations of the American College of Cardiology/American Heart Association (JA Joglar et al. Circulation 2024; 149:e1). Recommendations for periprocedural management of oral anticoagulant therapy vary with the anticoagulant, the bleeding risk of the patient and the procedure, the patient’s thromboembolic risk (CHA2DS2-VASc score), the presence of a mechanical valve, and for some anticoagulants, the patient’s renal function. These recommendations are provided in detail in both of the above-cited guidelines.