Iloprost (Aurlumyn) for Frostbite
Iloprost (Aurlumyn) for Frostbite
July 22, 2024 (Issue: 1707)
The FDA has approved Aurlumyn (Eicos Sciences),
an IV formulation of the prostacyclin analog iloprost,
to reduce the risk of digit amputation in adults
with severe frostbite. Iloprost is the first drug to be
approved by the FDA for treatment of...more
- RL Sheridan et al. Diagnosis and treatment of frostbite. N Engl J Med 2022; 386:2213. doi:10.1056/nejmra1800868
- S Hickey et al. Guidelines for thrombolytic therapy for frostbite. J Burn Care Res 2020; 41:176. doi:10.1093/jbcr/irz148
- J Lee and MCSS Higgins. What interventional radiologists need to know about managing severe frostbite: a meta-analysis of thrombolytic therapy. AJR Am J Roentgenol 2020; 214:930. doi:10.2214/ajr.19.21592
- J Gauthier et al. Iloprost for the treatment of frostbite: a scoping review. Int J Circumpolar Health 2023; 82:2189552. doi:10.1080/22423982.2023.2189552
- E Cauchy et al. A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite. N Engl J Med 2011; 364:189. doi:10.1056/nejmc1000538
- AK Lorentzen et al. Interventions for frostbite injuries. Cochrane Database Syst Rev 2020; 12:CD012980. doi:10.1002/14651858.cd012980.pub2
- SE McIntosh et al. Wilderness Medical Society clinical practice guidelines for the prevention and treatment of frostbite: 2024 update. Wilderness Environ Med 2024; 35:183. doi:10.1177/10806032231222359
The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.
Would you like to read the rest of this article? Gain access below.
Subscribe
Subscriptions to
The Medical Letter on Drugs and Therapeutics include:
- Print version published and mailed biweekly (26 issues/year)
- Unlimited online access to current and past issues (1988 - present)
- Mobile App
- FREE online per issue CME/CE
Purchase this article:
Title: Iloprost (Aurlumyn) for Frostbite
Article code: 1707b
Gain access through your organization
Ask your librarian to consider an Institutional Subscription to The Medical Letter.
