The Medical Letter on Drugs and Therapeutics
FROM
ISSUE1747
ISSUE1747
February 2, 2026
Lumateperone (Caplyta) for Adjunctive Treatment of Depression
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Lumateperone (Caplyta) for Adjunctive Treatment of Depression
February 2, 2026 (Issue: 1747)
The FDA has approved the second-generation
antipsychotic drug lumateperone (Caplyta — Intra-Cellular Therapies) for adjunctive treatment of major
depressive disorder (MDD) in adults. Lumateperone
was approved earlier for treatment of...more
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