The Medical Letter on Drugs and Therapeutics
FROM
ISSUE 1158
ISSUE 1158
June 8, 2003
Drug Interactions
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June 8, 2003 (Issue: 1158)
Changes caused by one drug in the absorption, distribution, metabolism or excretion of another may lead to a pharmacokinetic adverse drug interaction (DN Juurlink et al, JAMA 2003; 289:1652). Additive drug interactions, such as vasodilation caused by both sildenafil (Viagra) and nitrates, can also have adverse effects.
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