The Medical Letter on Drugs and Therapeutics
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1161
Bortezomib (Velcade) for Multiple Myeloma
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Bortezomib (PS341; Velcade Millenium), the first proteasome inhibitor, has received accelerated approval from the FDA for treatment of refractory multiple myeloma. This review includes descriptions of the mechanism of action, pharmacokinetics, adverse effects, and dosage and cost of bortezomib, outlines the results of clinical studies, and concludes with an overall assessment of the drug's effectiveness. ... more
     
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Title: Bortezomib (Velcade) for Multiple Myeloma
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