The Medical Letter on Drugs and Therapeutics
FROM
ISSUE
1261
A New Sunscreen Agent
The full article is available to subscribers Subscriber Login   
Revised 10/10/07: See last two sentences in the USE OF SUNSCREENS paragraph regarding sunscreens and DEET.

Ecamsule (terephthalylidene dicamphor sulfonic acid), the first new sunscreen agent to be approved by the FDA in 18 years, is now available in the US in a moisturizer called Anthelios SX. Ecamsule has been used in Canada and Europe for more than 10 years.

ULTRAVIOLET (UV) RADIATION — Solar UV radiation capable of injuring the skin is classified by wavelength into UVA1 (340-400 nm), UVA2 (320-340 nm) and UVB (290-320 nm). UVA, which makes up 95% of terrestrial UV radiation and penetrates into the dermis, is primarily responsible for photoaging and phototoxicity. UVB, which is largely absorbed in the epidermis, is responsible for most of the erythema of sunburn, but UVA2 is also erythemogenic. Both UVA and UVB can damage DNA, suppress immune function and cause skin cancer in animals.1 UVB is present primarily in spring and summer in temperate climates and is strongest at midday; UVA is ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

Would you like to read the rest of this article?  Gain access below.

Subscribe
Subscriptions to The Medical Letter on Drugs and Therapeutics include:
  • Print version published and mailed biweekly (26 issues/year)
  • Unlimited online access to current and past issues (1988 - present)
  • Mobile App for iOS, Android, and Kindle Fire
  • FREE online per issue CME/CE
Purchase this article:
Title: A New Sunscreen Agent
Article code: 1261a
 Electronic, downloadable article - $45
Gain access through your organization
Ask your librarian to consider an Institutional Subscription to The Medical Letter.
Recommend to your librarian