The Medical Letter on Drugs and Therapeutics
FROM
ISSUE
1267
Probiotics
The full article is available to subscribers Subscriber Login   

Probiotics are live, nonpathogenic microorganisms (usually bacteria or yeasts) that have been used for centuries for their potential health benefits. They are currently marketed for prevention and treatment of a variety of disorders, including diarrhea, irritable bowel syndrome and inflammatory bowel disease.

MECHANISM OF ACTION — Several mechanisms of action have been proposed to explain how probiotics could have beneficial effects. Acetic, lactic and propionic acid produced by Lactobacillus can lower intestinal pH and inhibit growth of pathogenic bacteria such as Escherichia coli and Clostridium spp. The presence of probiotics in the intestinal tract may physically or chemically prevent adhesion and colonization of pathogenic bacteria. They may also induce or enhance immune responses.1 Saccharomyces boulardii, which is a yeast, has been shown to inhibit ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

Would you like to read the rest of this article?  Gain access below.

Subscribe
Subscriptions to The Medical Letter on Drugs and Therapeutics include:
  • Print version published and mailed biweekly (26 issues/year)
  • Immediate Online access to current issue and archives from 1988 to the present
  • Mobile access to our mobile site and free apps for iOS, Android and Kindle
  • FREE online per issue CME/CE
Free trial offer
3 Free Issues of The Medical Letter on Drugs and Therapeutics mailed to your home or office PLUS online access.
Try a Free Trial Subscription
Purchase this article:
Title: Probiotics
Article code: 1267b
 Electronic, downloadable article - $25