The Medical Letter on Drugs and Therapeutics
Gluten-Free Drugs for Celiac Disease Patients
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Celiac disease is a chronic autoimmune disorder caused by a genetic intolerance to gluten that occurs in about 1% of the population.1 The main form of treatment is a lifelong gluten-free diet.

CELIAC DISEASE — Although originally described in young children as a malabsorption syndrome characterized by diarrhea, steatorrhea and failure to thrive, particularly after cereals are first introduced, presentations in older children, adolescents and adults with diarrhea or non-gastrointestinal signs and symptoms (such as iron-deficiency anemia, metabolic osteopathy, short stature, neurologic symptoms, type 1 diabetes and dermatitis herpetiformis) are now more common.2 Potential complications of celiac disease include intestinal adenocarcinoma, enteropathy-associated T-cell lymphoma and refractory sprue. The trigger for these signs, symptoms and complications is exposure of the ... more      

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Title: Gluten-Free Drugs for Celiac Disease Patients
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