The Medical Letter on Drugs and Therapeutics
Vitamins for Cataract Prevention
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Cataracts are the leading cause of blindness worldwide because cataract surgery is not available to most people in developing countries. In the US, it has been projected that by 2015 cataract surgery will account for more than 10% of Medicare’s annual budget. Many observational studies have shown that well-nourished people have a lower incidence and slower progression of cataracts than those who are not well-nourished, but cause and effect have been difficult to establish. Three large, prospective, randomized, intervention studies have now been published.1

THE AGE-RELATED EYE DISEASE STUDY (AREDS) — A double-masked, randomized, placebocontrolled trial in 4757 patients, most between 55 and 80 years old, found that beta carotene 15 mg, vitamin C 500 mg and vitamin E 400 IU taken for an average of 6.3 years had no statistically significant effect in reducing the risk of progression of lens opacities ... more      

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Title: Vitamins for Cataract Prevention
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