The Medical Letter on Drugs and Therapeutics
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1291
ECGs Before Stimulants in Children
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The American Heart Association (AHA) recently published a statement saying that it would be reasonable to obtain an electrocardiogram (ECG) in children being evaluated for stimulant drug therapy for attention deficit hyperactivity disorder (ADHD).1 A subsequent news release in conjunction with the American Academy of Pediatrics provided a clarification, saying that it would be reasonable to consider obtaining an ECG in such children.

BACKGROUND — Reports of sudden unexpected death in 14 children and 6 adults in the US led Health Canada to suspend sales of Adderall XR, a mixture of amphetamine salts used to treat ADHD. That decision was later reversed. The FDA did not act to limit sales of the drug because the number of sudden unexpected deaths was no greater than expected, given the large number of people taking the drug. However, since 5 of the children who died had structural ... more      

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Title: ECGs Before Stimulants in Children
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