The Medical Letter on Drugs and Therapeutics
FROM
ISSUE
1337
Cost of Topical Products for Tinea Pedis
Subscribers: Log in to read full article.  Not a subscriber?  Subscribe or purchase article.

A Medical Letter reader recently received a diagnosis of athlete’s foot and a prescription for Naftin gel, for which his pharmacy charged $145, and his insurance company required a $70 copay because this formulation was not included in its formulary. Do patients need to pay prices like these to treat tinea pedis?

DRUGS FOR TINEA PEDIS — Most dermatologists prescribe either an allylamine, benzylamine or imidazole topical antifungal to treat tinea pedis. All three inhibit synthesis of ergosterol, an essential component of fungal cell membranes. Allylamines are more active in vitro than imidazoles against the dermatophytes that cause the disease.

CLINICAL TRIALS — Only a few clinical trials have compared topical antifungal drugs with each other, and none have found the sponsor’s drug inferior to the comparator. A 1993 double-blind randomized trial (sponsored by the manufacturer ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

Would you like to read the rest of this article?  Gain access below.

Subscribe
Subscriptions to The Medical Letter on Drugs and Therapeutics include:
  • Print version published and mailed biweekly (26 issues/year)
  • Unlimited online access to current and past issues (1988 - present)
  • Mobile App for iOS, Android, and Kindle Fire
  • FREE online per issue CME/CE
Purchase this article:
Title: Cost of Topical Products for Tinea Pedis
Article code: 1337c
 Electronic, downloadable article - $45
Gain access through your organization
Ask your librarian to consider an Institutional Subscription to The Medical Letter.
Recommend to your librarian