The Medical Letter on Drugs and Therapeutics
Preservation of Ovarian Function During Chemotherapy
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Chemotherapy can result in premature menopause and infertility in young women. Pretreatment fertility counseling followed by appropriate action may prevent some of these undesirable consequences.1,2

FERTILITY PRESERVATION — Embryo cryopreservation after in vitro fertilization remains the standard of care for fertility preservation in women, but oocyte cryopreservation is also used. Ovarian tissue freezing for later transplantation, while available at some centers, is experimental, and data on its efficacy are limited to case reports.3-5 All of these techniques are invasive, and none would prevent premature menopause, which can lead to early osteoporosis and coronary artery disease.

OVARIAN SUPPRESSION — Two small observational studies suggest that oral contraceptive pills may preserve ovarian function,6,7 ... more      

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Title: Preservation of Ovarian Function During Chemotherapy
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