The Medical Letter on Drugs and Therapeutics
Bronchial Thermoplasty for Asthma
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The FDA has approved the marketing of the Alair Bronchial Thermoplasty System (Asthmatx) for treatment of severe persistent asthma in patients ≥18 years old whose asthma is not well controlled with inhaled corticosteroids and long-acting beta2-agonists.

DRUGS FOR ASTHMA — Current treatment options for patients with severe asthma include inhaled corticosteroids, long-acting beta2-agonists (LABAs), leukotriene receptor antagonists and, for the most refractory disease, chronic oral corticosteroids. In patients with persistent allergic asthma, omalizumab (Xolair) can be tried in patients ≥12 years old.1

RATIONALE FOR THERMOPLASTY — Patients with asthma may have hypertrophy of smooth muscle that narrows the airway. Bronchial thermoplasty reduces airway smooth muscle mass and widens the airway.

THE PROCEDURE — ... more      

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Title: Bronchial Thermoplasty for Asthma
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