The Medical Letter on Drugs and Therapeutics
Miconazole (Oravig) for Oropharyngeal Candidiasis
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The FDA has approved a buccal tablet formulation of miconazole (Oravig – Strativa) for local treatment of oropharyngeal candidiasis in adults. Miconazole has been available for many years in topical formulations for treatment of superficial fungal infections and vulvovaginal candidiasis.1

OROPHARYNGEAL CANDIDIASIS — Clotrimazole troches or nystatin suspension are often used for initial treatment of mild to moderate oropharyngeal candidiasis. Compliance can be a problem because of the need for multiple doses, and recurrence is common. For treatment of recurrent or more severe disease, systemic fluconazole is often used, but development of resistance has been reported.2

PHARMACOLOGY — Miconazole is an azole antifungal with activity against many species of Candida, including some resistant to fluconazole.3 ... more      

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Title: Miconazole (Oravig) for Oropharyngeal Candidiasis
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