The Medical Letter on Drugs and Therapeutics
Alcaftadine (Lastacaft) for Allergic Conjunctivitis
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Alcaftadine (Lastacaft – Allergan), an ophthalmic H1-antihistamine, has been approved by the FDA for prevention of itching associated with allergic conjunctivitis in patients > 2 years old.

TREATMENT OF ALLERGIC CONJUNCTIVITIS — Allergic conjunctivitis is the most common form of ocular allergy. The main symptom, itching, can be relieved by an oral H1-antihistamine such as cetirizine (Zyrtec, and others; available over the counter) or fexofenadine (Allegra, and others; available over the counter). Ophthalmic antihistamines (Table 1) are also effective and have a more rapid onset of action (within a few minutes) than the oral drugs. Ophthalmic mast-cell stabilizers cromolyn (Crolom, and others), lodoxamide (Alomide), nedocromil (Alocril) and pemirolast (Alamast) have a slower onset ... more      

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Title: Alcaftadine (Lastacaft) for Allergic Conjunctivitis
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