The Medical Letter on Drugs and Therapeutics
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1365
Capsaicin Patch (Qutenza) for Postherpetic Neuralgia
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The FDA has approved a topical 8% patch formulation of capsaicin (Qutenza – NeurogesX), available only by prescription, for local treatment of postherpetic neuralgia. Postherpetic neuralgia occurs after herpes zoster in about one third of patients ≥60 years old and can persist for months or even years.1

STANDARD TREATMENT — Opioids and topical analgesics such as lidocaine (Lidoderm) are commonly used to treat postherpetic neuralgia. Oral nonopioid analgesics generally have not been effective for this indication. The anticonvulsants pregabalin (Lyrica) and gabapentin (Neurontin, and others) are FDA-approved for treatment of postherpetic neuralgia.2 Tricyclic antidepressants have been used as an adjunct, but their use has been limited by anticholinergic side effects. Lower-strength (0.025%-0.15%) cream, liquid ... more      

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Title: Capsaicin Patch (Qutenza) for Postherpetic Neuralgia
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