The Medical Letter on Drugs and Therapeutics
New Treatments for Keratoconus
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Keratoconus is a fairly common, progressive, noninflammatory, corneal-thinning disorder in which the cornea has a conical shape. Rigid gas permeable (RGP) contact lenses or corneal transplantation are effective treatments, but intracorneal ring segments and collagen cross-linking procedures offer some new alternatives in the management of the disease.

THE DISEASE — Keratoconus has a variable presentation, ranging from myopic astigmatism requiring only spectacle correction to significant corneal stromal thinning, corneal protrusion, and corneal scarring requiring corneal transplantation. It has an incidence of 1 in 2000 and usually appears in puberty and progresses through the 3rd or 4th decade. Some studies have suggested an association with autoimmune disorders, but most patients have isolated bilateral keratoconus.

STANDARD TREATMENT — Management of early keratoconus generally begins with ... more      

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Title: New Treatments for Keratoconus
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