The Medical Letter on Drugs and Therapeutics
Intraosseous Infusion for Rapid Vascular Access
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The intramedullary venous plexus of cancellous bone marrow does not collapse in patients who are dehydrated or in shock. Intraosseous (IO) infusion through an intramedullary cannula has effectively replaced central venous catheterization (CVC) as the method of choice for rapid vascular access in both adults and children when peripheral veins are inaccessible.1,2 Absorption of fluids into the central circulation with IO infusion is equivalent to absorption from IV sites, and IO access can be achieved more rapidly and with a higher success rate than CVC.3

EFFICACY OF IO INFUSION DEVICES — All of the devices in Table 1 can provide vascular access in less than 2 minutes. In one study with the FAST 1 sternal IO device, the average time to access was 67 seconds.4 The average time for peripheral ... more      

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Title: Intraosseous Infusion for Rapid Vascular Access
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