The Medical Letter on Drugs and Therapeutics
An OTC Corticosteroid Nasal Spray for Allergic Rhinitis
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The FDA has approved the over-the-counter (OTC) sale of Nasacort Allergy 24HR (Sanofi), a triamcinolone acetonide nasal spray previously available only by prescription as Nasacort AQ. The OTC product, which is scheduled to be marketed in the spring of 2014, will be the first corticosteroid nasal spray that can be purchased without a prescription in the US. Nasacort Allergy 24HR is approved for use in patients ≥2 years old with nasal allergy symptoms.

CLINICAL USE — Intranasal corticosteroids are more effective than intranasal antihistamines for prevention and relief of allergic rhinitis symptoms, including itching, sneezing, discharge, and congestion, and are the drugs of choice for moderate-to-severe disease.1 Most of these agents are effective when given once or twice daily. The onset of action typically occurs within 12 hours, but maximal effects may not ... more      

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Title: An OTC Corticosteroid Nasal Spray for Allergic Rhinitis
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