The Medical Letter on Drugs and Therapeutics
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1431
Ferric Carboxymaltose (Injectafer) for Iron Deficiency Anemia
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The FDA has approved ferric carboxymaltose (Injectafer – American Regent), a 2-dose intravenous iron replacement product, for treatment of iron deficiency anemia (IDA) in adults who cannot tolerate or have had an unsatisfactory response to oral iron and in those who have non-dialysis-dependent chronic kidney disease (CKD). It is the sixth IV iron product approved in the US.

IV IRON SUPPLEMENTATION — IV iron is prescribed for patients with IDA who cannot absorb or tolerate oral iron or who have unresolved bleeding.1 For patients with non-dialysis-dependent CKD, the route of iron administration is based on the severity of iron deficiency, availability of venous access, response to prior therapies, patient adherence, and cost.2 Most IV iron preparations are given in 3-10 infusions over multiple weeks. Ferumoxytol (Feraheme) ... more      

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