The Medical Letter on Drugs and Therapeutics
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1460
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Drugs for Chronic Heart Failure
Superseded by The Medical Letter "Drugs for Chronic Heart Failure" - Issue 1569, April 8, 2019
Heart failure is usually associated with left ventricular dysfunction. According to recent guidelines, patients with a left ventricular ejection fraction (LVEF) ≤40% are considered to have heart failure with reduced ejection fraction (HFrEF) or systolic heart failure. Patients with a LVEF ≥50% and symptoms of heart failure are considered to have heart failure with preserved ejection fraction (HFpEF) or diastolic heart failure; there is little evidence that drug treatment improves clinical outcomes in these patients. The treatment of acute heart failure is not included here.
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