The Medical Letter on Drugs and Therapeutics
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ISSUE
1461
Peramivir (Rapivab): An IV Neuraminidase Inhibitor for Treatment of Influenza
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The FDA has approved peramivir (Rapivab – BioCryst), an IV neuraminidase inhibitor administered as a single dose, for treatment of acute uncomplicated influenza in patients ≥18 years old who have had symptoms for no more than 2 days. Peramivir was available temporarily in the US during the 2009-2010 influenza season under an emergency use authorization for treatment of hospitalized patients. It has been available in some Asian countries since 2010. Peramivir is the third neuraminidase inhibitor to be approved in the US. Oseltamivir (Tamiflu), which is taken orally, and zanamivir (Relenza), which is inhaled, are approved for prophylaxis and treatment of influenza in children and adults.1

TREATMENT OF INFLUENZA — Neuraminidase inhibitors are currently the drugs of choice for treatment of patients with influenza; almost all of the influenza A and B viruses ... more      

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Title: Peramivir (Rapivab): An IV Neuraminidase Inhibitor for Treatment of Influenza
Article code: 1461b
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