The Medical Letter on Drugs and Therapeutics
Racemic Amphetamine Sulfate (Evekeo) for ADHD
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The FDA has approved racemic amphetamine sulfate (Evekeo – Arbor) for oral treatment of attention-deficit/hyperactivity disorder (ADHD) in children ≥3 years old. It was also approved for treatment of narcolepsy in patients ≥6 years old and for short-term treatment of obesity in patients ≥12 years old.

AMPHETAMINES FOR ADHD ― Amphetamines generally have been as effective as methylphenidate in decreasing overactivity, impulsivity, and inattention in children with ADHD. Some children who have not responded to methylphenidate may respond to an amphetamine, and vice versa. Dextroamphetamine, mixed amphetamine salts, and lisdexamfetamine dimesylate, an oral prodrug of dextroamphetamine, vary in their durations of action, but appear to be similar in efficacy.1 All stimulants used for treatment of ADHD are classified as schedule II controlled substances by ... more      

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Title: Racemic Amphetamine Sulfate (Evekeo) for ADHD
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