The Medical Letter on Drugs and Therapeutics
FROM
ISSUE 1487
ISSUE 1487
February 1, 2016
Drugs for Acne
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February 1, 2016 (Issue: 1487)
Superseded by The Medical Letter "Drugs for Acne" - Issue 1612, November 30, 2020The pathogenesis of acne is multifactorial: follicular hyperkeratinization, bacteria, sebum production, androgens, and inflammation all play a role. The gram-positive microaerophilic bacteria Propionibacterium acnes promotes development of acne lesions by secreting chemotactic factors that attract leukocytes to the follicle, causing inflammation. ... more
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