The Medical Letter on Drugs and Therapeutics
FROM
ISSUE 1487
ISSUE 1487
February 1, 2016
Drugs for Acne
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February 1, 2016 (Issue: 1487)
The pathogenesis of acne is multifactorial: follicular
hyperkeratinization, bacteria, sebum production,
androgens, and inflammation all play a role. The gram-positive
microaerophilic bacteria Propionibacterium
acnes promotes development of acne lesions by
secreting chemotactic factors that attract leukocytes
to the follicle, causing inflammation.
... more
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