The Medical Letter on Drugs and Therapeutics
FROM
ISSUE
1487
Drugs for Acne
The full article is available to subscribers Subscriber Login   

The pathogenesis of acne is multifactorial: follicular hyperkeratinization, bacteria, sebum production, androgens, and inflammation all play a role. The gram-positive microaerophilic bacteria Propionibacterium acnes promotes development of acne lesions by secreting chemotactic factors that attract leukocytes to the follicle, causing inflammation.

TOPICAL THERAPY — Salicylic Acid – Widely available over the counter (OTC), topical salicylic acid is a well-tolerated keratolytic agent that can be used alone or in combination with other drugs such as benzoyl peroxide.

Benzoyl Peroxide – The oxidizing agent benzoyl peroxide is available in a wide variety of OTC and prescription preparations for treatment of mild to moderate acne. Its effect is primarily due to its antibacterial activity against P. acnes. Benzoyl peroxide is often used in combination with topical or oral antibiotics. It ... more      

The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.

Would you like to read the rest of this article?  Gain access below.

Subscribe
Subscriptions to The Medical Letter on Drugs and Therapeutics include:
  • Print version published and mailed biweekly (26 issues/year)
  • Unlimited online access to current and past issues (1988 - present)
  • Mobile App for iOS, Android, and Kindle Fire
  • FREE online per issue CME/CE
Purchase this article:
Title: Drugs for Acne
Article code: 1487a
 Electronic, downloadable article - $45
Gain access through your organization
Ask your librarian to consider an Institutional Subscription to The Medical Letter.
Recommend to your librarian